Resident Evil Requiem has various major boss fights spread across Leon and Grace’s campaigns. Some bosses appear during Grace’s sections while most show up when you’re playing as Leon. Each boss has its own attack patterns and weak spots that you need to learn to survive. Here’s every boss in Resident Evil Requiem and basic strategies for beating them.

All Resident Evil Requiem Bosses
| Boss Name | Character | Location |
|---|---|---|
| The Girl | Grace | Care Center |
| Chunk | Leon, Grace | Care Center Attic |
| Blister Borne | Leon | Chapel |
| The Girl | Grace | Water Treatment Plant |
| Emily | Leon | Care Center Basement |
| Titan Spinner | Leon | Ruined Building |
| Victor and Garmrs | Leon | Highway |
| Super Tyrant (Mr. X) | Leon | Basketball Court |
| Plant 43 | Leon | Blackthorn Station |
| The Commander | Leon | ARK Facility |
| Victor (Final Form) | Leon | ARK Facility |
The Girl
Grace fights this ghost-like enemy twice. The first time happens at the Care Center where you can’t kill her – just solve puzzles and run to lit areas since she hates light. The second fight takes place at the Water Treatment Plant. Turn on three power switches around the building to open the roof. Once sunlight hits her, shoot to finish the job. Use bottles to distract her and throw Molotovs if she gets close.

Chunk
Leon picks up a shotgun right before this fight starts. This fat monster moves slowly but hits hard. Shoot his oversized head with the shotgun for maximum damage. When he falls down, switch to your hatchet and hit him three times. Repeat this pattern – shoot the head until he drops, then melee attack. The arena has extra shotgun shells scattered around if you run low.

Blister Borne
This big enemy has blisters covering its body. Pop all the cysts to win. Each time you destroy one, zombies turn into faster Blister Head zombies. Kill the Blister Heads first since they’re dangerous. Aim for the back cyst early since it’s harder to hit later. Use the explosive barrels in the chapel to clear zombie groups quickly.

Emily
Emily transforms into a monster during the basement section. Leon has to put her down. This fight is straightforward – keep shooting until she stops moving. Save your stronger weapons for later bosses since Emily doesn’t require special tactics. Just maintain distance and fire consistently.

Titan Spinner
A giant spider attacks Leon inside a ruined building. Shoot its mouth when the spider faces you directly. After dealing enough damage, it collapses and exposes a weak spot on its back. Use your Requiem pistol on the back cyst about 4-5 times to end the fight. Red explosive containers around the room can knock it down instantly if you hit them.

Victor and Garmrs
This motorcycle chase has Victor shooting rockets while mutant dogs attack. Shoot the closest dog first since they attack at close range. When you see a red arrow flash above Victor’s head, shoot him quickly to stop his rocket launcher. Keep your gun reloaded between attacks. The final section is a quick draw – just shoot Victor when prompted.

Super Tyrant (Mr. X)
You first see Mr. X at the police station but can’t fight him there. The real battle happens near a basketball court. His glowing heart is the only weak spot. Shoot the heart repeatedly with your strongest guns. Mr. X stops before attacking, giving you time to aim. When he kneels down, a button prompt appears – press it to stab his heart with your hatchet. Do this 2-3 times to win.

Plant 43
A massive plant blocks the ARK entrance. Wait for its center bud to open, then shoot inside with SMGs or shotguns. The side vines telegraph their attacks by rising up first, so stay mobile. After enough damage, explosive tanks drop below the plant. Shoot any tank to trigger an explosion that kills the plant instantly.

The Commander
This boss only takes damage from hatchet attacks after successful parries. Your guns won’t work at all. Watch for his attack animations and press the parry button at the right moment. Each successful parry lets you counterattack with your hatchet. The timing is strict, so focus entirely on learning his patterns. Beating him rewards you with the Mortal Edge, a better hatchet.

Victor (Final Form)
The last boss has two phases. Phase one shows Victor with a mutated tentacle arm. Parry all his attacks and shoot him after each deflection. Eventually he picks up a rocket launcher – shoot him to make him drop it, then use the launcher against him. Phase two transforms him into a Nemesis-like creature. Red weak spots appear all over his body. Shoot these spots with rapid-fire weapons like SMGs. You can still parry his attacks in this form.

Resident Evil Requiem’s boss fights test your aim, timing, and resource management throughout the entire game. Each fight introduces new mechanics or challenges that prepare you for the final showdown against Victor.